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ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 685-698 doi: 10.1007/s11684-022-0942-1

Abstract: Acyl-CoA synthetase long chain family member 5 (ACSL5), is a member of the acyl-CoA synthetases (ACSs) family that activates long chain fatty acids by catalyzing the synthesis of fatty acyl-CoAs.The dysregulation of ACSL5 has been reported in some cancers, such as glioma and colon cancers.However, little is known about the role of ACSL5 in acute myeloid leukemia (AML).Additionally, triacsin c, a pan-ACS family inhibitor, inhibited cell growth and robustly induced cell

Keywords： acute myeloid leukemia     acyl-CoA synthetase long chain family member 5     Wnt3a     palmitoylation     ABT-199    

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Keratin 5-Cre-driven deletion of

Jun Yang, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu, Xue Zhang

Frontiers of Medicine 2020, Volume 14, Issue 3,   Pages 305-317 doi: 10.1007/s11684-019-0722-8

Abstract: In this study, we generated a keratin 5-Cre-driven epidermis-specific conditional knockout mutant inRNA-Seq analysis indicated that Sprr2d, a member of the small proline-rich protein 2 family, in the skinQuantitative reverse-transcription polymerase chain reaction showed that other genes had a similar

Keywords： acne inversa mouse model     interleukin 1 family     member 6     small proline rich protein 2D     key inflammatory    

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Responses of bacterial strains isolated from drinking water environments to N-acyl-L-homoserine lactones

Zhuoying WU, Qing WANG, Feng GUO, Shenghua ZHANG, Qipei JIANG, Xin YU

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 2,   Pages 205-214 doi: 10.1007/s11783-013-0492-5

Abstract: properties of the strains were investigated: bacterial biofilm formation capacity, QS signal molecule N-acyl-L-homoserinelactones (AHLs) production ability, and responses to AHLs and AHL analogs, 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) and 2(5H)-furanone.

Keywords： drinking water distribution systems (DWDS)     biofilm     quorum sensing (QS)     N-acyl-L-homoserine lactones (AHLs)     (dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)     2(5H)-furanone    

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Benzene alkylation with long chain olefins catalyzed by ionic liquids: a review

QIAO Congzhen, CAI Yonghong, GUO Quanhui

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 3,   Pages 346-352 doi: 10.1007/s11705-008-0045-9

Abstract: The introduction of ionic liquids to alkylation process gives a choice for “green production” in the petrochemical and detergent industry. A lot of papers and patents have been published using chloroaluminate ionic liquid as a novel catalyst for alkylation with high reactivity and easy separation from reactants. These included the acidity, characterization, determination and catalysis technologies in batch and continuous operation mode for different scales. According to published data and several results of pilot alkylation,including the authors’ experience,the prospect of chloroaluminate ionic liquids for commercials was also discussed. It has been pointed out that there still are many difficulties and challenges to be overcome for commercial application of the ionic liquid catalyst.

Keywords： different     petrochemical     characterization     introduction     chloroaluminate    

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Continuous reaction performances of benzene alkylation with long chain olefins catalyzed by ionic liquid

QIAO Congzhen, LI Chengyue

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1,   Pages 69-73 doi: 10.1007/s11705-008-0014-3

Abstract: mixing-reacting-separating-recycling small experimental setup,the continuous reaction performances of benzene alkylation with longchain olefins catalyzed by [BMIM]Cl-AlCl ionic liquid were investigated.

Keywords： stability     different     hypecritical     compulsive mixing-reacting-separating-recycling     non-benzene    

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The Present Situation and Prospect of China's Space-entering Capacity

Long Lehao,Wang Xiaojun,Guo Linli

Strategic Study of CAE 2006, Volume 8, Issue 11,   Pages 25-28

Abstract: the launching system in space activities abroad, and analyzes the situation of China´s “Long-MarchThe paper also proposes 5 development directions for enhancing China ´s spaceentering capacity：

Keywords： space activities     “Long-March” rocket family     manned lunar landing     reusable launching vehicles    

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Long-term correction of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composedof the human heavy chain and the rat light chain

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 584-595 doi: 10.1007/s11684-021-0844-7

Abstract: Plasmids containing human FVIII heavy chain (hHC), human light chain (hLC), and rat light chain (rLC)

Keywords： hemophilia A     adeno-associated virus (AAV)     human/rat hybrid factor VIII     gene therapy     dual chain strategy    

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The Integration Model of Closed-Loop Supply Chain Resource Allocation Considering Remanufacturing

Xiao-qiu Shi,Yan-yan Li,Wei Long

Frontiers of Engineering Management 2016, Volume 3, Issue 2,   Pages 132-135 doi: 10.15302/J-FEM-2016026

Abstract: For the remanufacturing supply chain, recycling and rebuilding of products form a reverse materials movementFor the characteristics of reverse logistics of remanufacturing supply chain, we propose a closed-loopsupply chain resource allocation model based on autonomous multi-entity.

Keywords： remanufacturing     supply chain     reverse logistics     resource allocation     integration model    

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Synthesis of ordered cerium-doped cubic mesoporous silica using long-chain ionic liquid as template

YUE Hongxia, ZHAO Hongmei, LIU Longjiang, WANG Siping, Ruan Qiong, WANG Tongwen

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 2,   Pages 135-139 doi: 10.1007/s11705-008-0031-2

Abstract: The long-chain ionic liquid 1-hexadecyl-3-methylimidazolium chloride (CmimCl) was used as a template

Keywords： mesoporous     CmimCl/Si     tendency     mesostructure     synthesis procedure    

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Optimal dome design considering member-related design constraints

Tugrul TALASLIOGLU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 5,   Pages 1150-1170 doi: 10.1007/s11709-019-0543-5

Abstract: This study proposes to optimize the design of geometrically nonlinear dome structures. A new Multi-objective Optimization Algorithm named Pareto Archived Genetic Algorithm (PAGA), which has an ability of integrating the nonlinear structural analysis with the provisions of American Petroleum Institute specification is employed to optimize the design of ellipse and sphere-shaped dome configurations. Thus, it is possible to investigate how the qualities of optimal designations vary considering the shape, size, and topology-related design variables. Furthermore, the computing efficiency of PAGA is evaluated considering six multi-objective optimization algorithms and eight quality measuring indicators. It is shown that PAGA has a capability of both exploring an increased number of pareto solutions and predicting a pareto front with a higher convergence degree. Moreover, the inclusion of shape-related design variables leads to a decrease in both the weights of dome structures and their load-carrying capacities. However, the designer easily determines the most requested optimal design through the archiving feature of PAGA. Thus, it is also demonstrated that the proposed optimal design procedure increases the correctness degree in the evaluation of optimal dome designs through the tradeoff analysis. Consequently, PAGA is recommended as an optimization tool for the design optimization of geometrically nonlinear dome structures.

Keywords： dome structure     geometric nonlinearity     multi-objective optimization     API RP2A-LRFD    

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Epidemiological study of a von Hippel-Lindau family in northwest China

Jingyao Zhang, Dapeng Wu, Hong Ai, Jigang Bai, Shunbin Dong, Qinling Yang, Kai Qu, Lei Zhou, Xinsen Xu, Chang Liu

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 378-385 doi: 10.1007/s11684-013-0276-0

Abstract: We encountered a large VHL family in northwest China and conducted a systematic screening of the familyFor the preliminary family screening, physical examination and abdomen B ultrasonography were performedA total of 63 lineal descendants in six generations were observed in the family (generations O, A, B,Therefore, follow-up checkups of the family should be focused on younger generations.Proper family screening protocols should be followed for the treatment of patients with VHL disease.

Keywords： von Hippel-Lindau disease     epidemiology     family screening     pancreatic endocrine tumor    

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Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1): A Multifaceted Cell Survival Factor that Review

Tamana Yousof, Jae Hyun Byun, Jack Chen, Richard C. Austin

Engineering 2023, Volume 20, Issue 1,   Pages 9-18 doi: 10.1016/j.eng.2022.05.014

Abstract:

Pleckstrin homology-like domain, family A, member 1 (PHLDA1) is a multifaceted intracellular proteinbelonging to the evolutionarily conserved pleckstrin homology-related domain family.

Keywords： ER-stress     Metabolism     Apoptosis     Cell survival     PHLDA1    

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The Advanced Gun Family——the birth of type 95 (5.8 mm) squad gun family

Duo Yingxian

Strategic Study of CAE 1999, Volume 1, Issue 2,   Pages 57-61

Abstract: So after a short period of cooperated work, a new advanced squad gun family has been developed basedThis guns family were already used to equip the army assigned to Hong Kong in January, 1997 and shall

Keywords： squad gun family     automatic rifle     machine rifle     assault rifle    

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A CO and CO

Guoxing Chen, Marc Widenmeyer, Binjie Tang, Louise Kaeswurm, Ling Wang, Armin Feldhoff, Anke Weidenkaff

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3,   Pages 405-414 doi: 10.1007/s11705-019-1886-0

Abstract: Their chemical compatibility, oxygen permeability, CO and CO tolerance, and long-term CO resistance

Keywords： structure     oxygen permeation membrane     CO2 and CO resistances     CO2 plasma resistance     long-term    

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Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Frontiers of Medicine   Pages 1006-1009 doi: 10.1007/s11684-023-1000-3

Abstract: Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Keywords： family craniofacial microsomia     Identification novel mutations    

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Title Author Date Type Operation

ACSL5, a prognostic factor in acute myeloid leukemia, modulates the activity of Wnt/-catenin signaling

Journal Article

Keratin 5-Cre-driven deletion of

Jun Yang, Lianqing Wang, Yingzhi Huang, Keqiang Liu, Chaoxia Lu, Nuo Si, Rongrong Wang, Yaping Liu, Xue Zhang

Journal Article

Responses of bacterial strains isolated from drinking water environments to N-acyl-L-homoserine lactones

Zhuoying WU, Qing WANG, Feng GUO, Shenghua ZHANG, Qipei JIANG, Xin YU

Journal Article

Benzene alkylation with long chain olefins catalyzed by ionic liquids: a review

QIAO Congzhen, CAI Yonghong, GUO Quanhui

Journal Article

Continuous reaction performances of benzene alkylation with long chain olefins catalyzed by ionic liquid

QIAO Congzhen, LI Chengyue

Journal Article

The Present Situation and Prospect of China's Space-entering Capacity

Long Lehao,Wang Xiaojun,Guo Linli

Journal Article

Long-term correction of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composedof the human heavy chain and the rat light chain

Journal Article

The Integration Model of Closed-Loop Supply Chain Resource Allocation Considering Remanufacturing

Xiao-qiu Shi,Yan-yan Li,Wei Long

Journal Article

Synthesis of ordered cerium-doped cubic mesoporous silica using long-chain ionic liquid as template

YUE Hongxia, ZHAO Hongmei, LIU Longjiang, WANG Siping, Ruan Qiong, WANG Tongwen

Journal Article

Optimal dome design considering member-related design constraints

Tugrul TALASLIOGLU

Journal Article

Epidemiological study of a von Hippel-Lindau family in northwest China

Jingyao Zhang, Dapeng Wu, Hong Ai, Jigang Bai, Shunbin Dong, Qinling Yang, Kai Qu, Lei Zhou, Xinsen Xu, Chang Liu

Journal Article

Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1): A Multifaceted Cell Survival Factor that

Tamana Yousof, Jae Hyun Byun, Jack Chen, Richard C. Austin

Journal Article

The Advanced Gun Family——the birth of type 95 (5.8 mm) squad gun family

Duo Yingxian

Journal Article

A CO and CO

Guoxing Chen, Marc Widenmeyer, Binjie Tang, Louise Kaeswurm, Ling Wang, Armin Feldhoff, Anke Weidenkaff

Journal Article

Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Journal Article